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AMUNDSEN

Evolocumab or Normal strategies to reach guidelines LDL objectives in patients with acute myocardial infarction treated by percutaneous coronary intervention

En cours

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objectif

A phase IV, multicentric, randomized, real-world pragmatic study that compares a strategy of early LDL reduction with anti-PCSK9 in patients defined as extreme high risk by 2019 ESC/EAS guidelines vs. Standard of Care as defined by the guidelines but also constrained by current drug availabilities in the different participating countries.

date de réalisation

2021

nombre de patients

1666

nombre de centres participants

International multicentric trial

type de financement

Private (AMGEN and Fonds de Dotation ACTION)

Référence

EUDRACT : 2021-000573-80

A study conducted by Fonds de Dotation ACTION.
Find out details and results on the dedicated page

AMUNDSEN conducted by Fonds de Dotation ACTION

Autres études

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AFLOAT

En cours


To assess if flecainide is more efficient than standard of care (control group) to prevent AF occurrence during the 3 months after PFO closure.
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ANCHOR

En cours


Demonstrate the superiority of an association of VA-ECMO and IABP with an optimal medical treatment compared with an optimal medical treatment only in cardiogenic shock AMI patients
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ARAMIS

En cours


Evaluation of Anakinra versus placebo in treatment of acute myocarditis and evaluation of the contuity of the reference treatment with IEC in patients without ventricular dysfunction ventriculaire.