Assessment of the Best Loading Dose of Clopidogrel to Blunt Platelet Activation, Inflammation and Ongoing Necrosis (ALBION)
Study Description
- To compare the Kinetics of inhibition of platelet aggregation (aggregometry) and platelet activation (flow cytometry) with different loading doses of clopidogrel ;
- To evaluate the effect on various parameters of inflammation and necrosis and the safety of these loading doses.
source clinicaltrials.gov
Publications
- Slow response to clopidogrel predicts low response
Anne Bellemain-Appaix, Gilles Montalescot, Johanne Silvain, Olivier Barthélémy, Farzin Beygui, Jean-Philippe Collet, Georges Sideris, Catherine Meuleman, Claire Bal-Dit-Sollier, Nicolas Lellouche, Grégory Ducrocq, Michel Slama, Olivier Milleron, Patrick Henry, Ludovic Drouet, ALBION Investigators
Publicated in Journal of the American College of Cardiology - A randomized comparison of high clopidogrel loading doses in patients with non-ST-segment elevation acute coronary syndromes: the ALBION (Assessment of the Best Loading Dose of Clopidogrel to Blunt Platelet Activation, Inflammation and Ongoing Necrosis) trial
Gilles Montalescot, Georges Sideris, Catherine Meuleman, Claire Bal-dit-Sollier, Nicolas Lellouche, Ph Gabriel Steg, Michel Slama, Olivier Milleron, Jean-Philippe Collet, Patrick Henry, Farzin Beygui, Ludovic Drouet, ALBION Trial Investigators
Publicated in Journal of the American College of Cardiology
