image dons

I make a donation

AFIJI

Register aiming at evaluating the impact of genetics on occuring of coronary diseases in young patients and the pharmacogenetic of clopidogrel and its impact on the prognosis of patients having had angioplasty

En cours

Colloquium "Rythme et conduction" (23 avril 2024)
Inscrivez-vous !

La Grande Journée du Coeur (13 juin 2023)
Attention : plus que quelques places restantes !

La Grande Journée du Coeur (mardi 13 juin 2023)
Les présentations sont en ligne

logo étude

objectif

Impact of genetics on occuring of coronary diseases in young patients and the pharmacogenetic of clopidogrel and its impact on the prognosis of patients having had angioplasty

date de réalisation

2009

nombre de patients

1200

nombre de centres participants

Monocentric (Cardiology institute, Pitié-Salpêtrière)

type de financement

Public (APHP)

Référence

-

Publications

  • Long-Term Evolution of Premature Coronary Artery Disease
    Jean-Philippe Collet, Michel Zeitouni, Niki Procopi, Jean-Sébastien Hulot, Johanne Silvain, Mathieu Kerneis, Daniel Thomas, Benoit Lattuca, Olivier Barthelemy, Yoan Lavie-Badie, Jean-Baptiste Esteve, Laurent Payot, Delphine Brugier, Izolina Lopes, Abdourahmane Diallo, Eric Vicaut, Gilles Montalescot, ACTION Study Group
    Publicated in Journal of the American College of Cardiology
  • CYP2C19 but not PON1 genetic variants influence clopidogrel pharmacokinetics, pharmacodynamics, and clinical efficacy in post-myocardial infarction patients
    Jean-Sébastien Hulot, Jean-Philippe Collet, Guillaume Cayla, Johanne Silvain, Frédérick Allanic, Anne Bellemain-Appaix, Stuart A Scott, Gilles Montalescot
    Publicated in Circulation : Cardiovascular Interventions
  • Cytochrome P450 2C19 polymorphism in young patients treated with clopidogrel after myocardial infarction: a cohort study
    Jean-Philippe Collet, Jean-Sébastien Hulot, Anna Pena, Eric Villard, Jean-Baptiste Esteve, Johanne Silvain, Laurent Payot, Delphine Brugier, Guillaume Cayla, Farzin Beygui, Gilbert Bensimon, Christian Funck-Brentano, Gilles Montalescot
    Publicated in The Lancet

Autres études

+

BIO-TAVI

En cours


Correlation between the platelet reactivity, the von Willebrand factor and bleeding and thrombotic events occuring during the year following TAVI
+

ARCACHON

En cours


To demonstrate the non-inferiority of a strategy of simple clinical follow-up (without non-invasive stress testing) in asymptomatic CAD patients with a prior history of coronary revascularization comp...
+

ANCHOR

En cours


Demonstrate the superiority of an association of VA-ECMO and IABP with an optimal medical treatment compared with an optimal medical treatment only in cardiogenic shock AMI patients